| Year | Events and Comments |
| Prior: | Timeline 191 BC- 220 BC |
| 221 BC | 221 BC – 205 BC: Ptolemy IV becomes Pharoah ▲ Winter 222-221 BC: Molon wintered in Ctesiphon (Polybius 5.45). 221 BC: Shih Huang Ti (259-210 BC), known as the “First Emperor” unified China for the first time. During his Chin Dynasty (221-210 BC), he initiated a centralized government, conducted a census and standardized the country’s currency, written language, laws, and weights & measures. He also began constructing the Great Wall of China. http://www.wisdomportal.com/History/HistoryDates-1.html A son, presumably the later coregent Antiochus, was born the following year (Polybius 5.55), i.e. 221 |
| 222 BC | 222 BC: Ptolemy III dies▼ Spring/Summer 222: Revolt of Molon, marriage of Antiochus III and Laodice (Polybius 5.43). 222 BC Rome: “Also three moons have appeared at once, for instance, in the consulship of Gnaeus Domitius and Gaius Fannius.” – Pliny, Natural History, Book II, Ch. 32 |
| 223 BC | The Seleucid king Seleucus III is assassinated▼ in Phrygia by members of his army while on campaign against Attalus of Pergamon. Succeeded by his brother Antiochus III.▲ 223 BC Rome: “At Ariminium a bright light like the day blazed out at night; in many portions of Italy three moons became visible in the night time.” – Dio Cassius, Roman History, Book I |
| 224 BC | 224 BC: The Romans, led by Consuls Gaius Atilius Regulus and Lucius Aemilius Papus, decisively defeat the coalition of Cisalpine Gallic tribes at the Battle of Telamon thus extending Roman influence over northern Italy. On the Roman side Gaius Atilius Regulus, commander of the Roman cavalry, is killed in the battle. On the Gallic side, one of the leaders, Concolitanus, is captured in battle, while the leader of the Gallic Gaesatae, Aneroëstes, kills himself when the battle is lost. |
| 225 BC | 225 BC: Seleucus II Callinicus Pogon:▼ is killed by a fall from his horse. He is succeeded by his elder son, Seleucus III Ceraunus▲, and later by his younger son Antiochus III the Great. 225 B.C. (227?) – Colossus of Rhodes toppled in earthquake |
| 226 BC | Seleucus Callinicus II, the son of Antiochus II & his half-sister Laodice, inherited the Seleucid throne when his mother poisoned his father (246 BC): In a series of disastrous defeats by the forces of Ptolemy III, he lost control of most of the Seleucid empire including the ancestral capitols of Seleucia & Antioch. He escaped capture from Ptolemy III by retreating to the interior of Asia Minor. But by delegating control of western Asia Minor to his treacherous brother Antiochus Hierax he lost that territory as well. Almost a decade after his humiliating defeat by the forces of his own relatives at Ancyra (235 BC) he managed to rout his brother but, in a final humiliation, died in a fall from his own horse. References: Josephus, Against Apion 1.206-207. Justin, Epitome 27.1-3. Appian, History of Rome: Syrian Wars 11.66. http://virtualreligion.net/iho/seleucus_2.html |
| 227 BC | 227 BC: The Macedonian regent, Antigonus III, marries the former king Demetrius II’s widow, Phthia, and assumes the crown thus deposing the young Philip V. |
| 228 BC | 228 BC: Archidamus V, king of Sparta of the Eurypontid line and brother of the murdered Spartan King Agis IV is assassinated returning to Sparta by the Agiad King Cleomenes III |
| 229 BC | The King of Macedonia, Demetrius II, dies.▼ His nephew, Antigonus III comes to the Macedonian throne as regent for his half-cousin and the future king Philip V▲, who is only ten years old. |
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| 235 BC | The gate of Janus is closed, as a symbol that Rome is at peace. |
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| 239 BC | |
| 240 BC | 240 BC, Eratosthenes measures the circumference of the earth. |
| 241 BC | Daniel 11:7-9 Prophecy fulfilled 246 BC -241 BC The Third Syrian War. Egypt Wins. The Revenge of Ptolemy Euergetes. Egypt Wins. Jerome in his commentary provides a detailed description of Ptolemy Euergetes conquest of the King of the North (Seleucus Callinicus). “He came up with a great army and advanced into the province of the king of the North, that is Seleucus Callinicus, who together with his mother Laodice was ruling in Syria, and abused them, and not only did he seize Syria, but also took Cilicia and the remoter regions beyond the Euphrates and nearly all of Asia as well. And then, when he heard that a rebellion was afoot in Egypt, he ravaged the kingdom of Seleucus and carried off as booty forty thousand talents of Silver, and also precious vessels and images of the gods to the amount of two and half thousand. Among them were the same images which Cambyses had brought to Persia at the time when he conquered Egypt. The Egyptian people were indeed devoted to idolatry, for when he had brought back their gods to them after so many years, they called him Euergetes (Benefactor). Daniel, The Key to Prophetic Revelation, John Walvoord, Pg. 260, Moody Press, Chicago, 1971 |
| 242 BC | 246 BC -241 BC The Third Syrian War. Egypt Wins. |
| 243 BC | 246 BC -241 BC The Third Syrian War. Egypt Wins. |
| 244 BC | 246 BC -241 BC The Third Syrian War. Egypt Wins. |
| 245 BC | 246-241 BC: The Third Syrian War. Egypt Wins. |
| 246 BC | 246 BC Greek Septuagint translated at the latest 246 BC: Laodice poisons Antiochus II Theos, Berenice Syra Phernophorus, and their infant son. Ptolemy II 285–246 BC Pharaoh of Egypt (arrow down) |
| 247 BC | Ptolemy II 285–246 BC Pharaoh of Egypt |
| 248 BC | Ptolemy II 285–246 BC Pharaoh of Egypt |
| 249 BC | Ptolemy II 285–246 BC Pharaoh of Egypt |
| 250 BC | Ptolemy II 285–246 BC Pharaoh of Egypt |
| Cont. | Click here for Timeline 251 BC – 280 BC |
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